Specifically, ICAM-1 is naturally incorporated into HIV-1 particles and enhances infection of LFA-1-expressing cells by stabilizing virus:cell interactions and supporting viral uptake [19]–[22], suggesting the incorporation of ICAM-1 into a virus that can target B cells, such as attenuated RABV strains [11], may help to enhance B cell infection and activation. Here, ICAM1 is linked to infection.