PARP1 and cancer: It was found that there was no significant association between PARP1 Val762Ala polymorphism and overall cancer risk (homozygous model: OR = 1.10, 95% CI = 0.96–1.25; heterozygous model: OR = 1.04, 95% CI = 0.96–1.12, recessive model: OR = 1.07, 95% CI = 0.95–1.20, dominant model: OR = 1.05, 95% CI = 0.97–1.14, and allele comparing: OR = 1.04, 95% CI = 0.98–1.11) (Table 2).