Our previous study, concerning the role of ELOVL2 in sperm maturation and male fertility, revealed that Elovl2−/− mice are infertile and heterozygote Elovl2+/− C57Bl/6 mice exhibit haploinsufficiency that gives rise to impaired spermatides in >99% of all male mice, which hindered us from obtaining homozygous Elovl2−/− mice (16). This evidence concerns the gene ELOVL2 and Infertility.