The level of VEGF-A expression did not correlate with vascularization in tumours: the analysis of tumours using the blood-vessel marker CD34 showed a similar vascular pattern in SC+ORT and ORT groups in primary tumours of both HCT116 (Fig. 4E,F) and SW48 (Fig. 4G,H) xenografts. This evidence concerns the gene CD34 and neoplasm.