ALBIA-NAM revealed able to perfectly discriminate the two populations of NAM patients, that is those with anti-HMGCR from those with anti-SRP aAbs (Figure 5C) and was negative for all other tested conditions, that is patients with different inflammatory/autoimmune conditions, DM, anti-tRNA synthetase Ab positive myositis or IBM, as well as patients with polyclonal hypergammaglobulinemia (see Additional file 3). Here, HMGCR is linked to inclusion body myositis.