TGM2 and neuroblastoma: As shown in Fig. 5, ER stress inducers increased TGase2 intracellular activity in most of the cell types evaluated, including human erythrocarcinoma (K562; Fig. 5A and B), cervical cancer (HeLa; Fig. 5C) and neuroblastoma (SH-SY5Y; Fig. 5D) cell lines.