To clarify whether XRCC2 expression is abnormal in human colon cancer, we analyzed XRCC2 expression in various tumor cell lines (colon cancer cell lines T84, HT29 and Lovo, breast cancer cell line MCF-7, esophageal cancer cell line EC9706) and normal HEK293 cell line. This evidence concerns the gene XRCC2 and colonic neoplasm.