Exposing breast carcinoma cells to 10 Gy also increased their sensitivity to MUC-1- (P = 0.001) and brachyury-specific T-cell lysis (P = 0.005), and significantly increased the sensitivity of lung and prostate carcinoma cells to CTLs specific for CEA (P = 0.0002, P < 0.0001, respectively), MUC-1 (P = 0.013, P = 0.006, respectively), and brachyury (P = 0.0002, P < 0.0001, respectively). This evidence concerns the gene TBX1 and breast carcinoma.