CD8A and ovarian carcinoma: While modest variation was observed in the estimated cell type differences between EOC cases and controls between the different study populations, particularly for CD8+ T-lymphocytes, this is not entirely unexpected given differences in the distribution of ovarian cancer histological subtypes between the study populations (Table 1; Teschendorff et al. [12]) and that variation in host immune responses to EOC has been shown to vary by histological subtype [58].