Using an established cutoff point of 7.25 μg/mL for patients with IBD (48), similar findings of elevated fecal lactoferrin in pediatric patients with UC (1880 ± 565 μg/mL) and CD (1701 ± 382 μg/mL) compared to healthy controls (1.17 ± 0.47 μg/mL; P < 0.001) were observed (49). This evidence concerns the gene LTF and irritable bowel syndrome.