KCNE1 and familial long QT syndrome: It took a further 8 years before the cloning of human and Xenopus KCNQ1 (then termed KvLQT1) was reported (Barhanin et al., 1996; Sanguinetti et al., 1996), KCNQ1 was linked to LQTS (Wang et al., 1996), and the KCNE1 functionality and IKs molecular correlate conundrums solved.