NR3C1 and major depressive disorder: In patients with depression without ELS, on the other hand we found significant correlation between GR and MR agonists and placebo: a significant positive correlation between AUC placebo vs. AUC fludrocortisone (R = 0.69; p < 0.05); AUC placebo vs. AUC dexamethasone (R = 0.53; p < 0.05); AUC fludrocortisone vs. AUC dexamethasone (R = 0.70; p < 0.01) and a negative significant correlation between CTQ scores vs. AUC dexamethasone (R = −0.78; p < 0.01) and CTQ scores vs. AUC fludrocortisone (R = −0.72; p < 0.01), see details in Tables 2 and 3.