However, when we control the data for depression scores (HAMD), BMI and use CTQ scores as continuous measures correlating with CAR AUC (nmol × h/L) after placebo vs. fludrocortisone vs. dexamethasone, the data retain the differences for ELS between after fludrocortisone (MR agonist) but not after dexamethasone (GR agonist), in the same line for depressive patients without ELS the data retain the differences for ELS between after fludrocortisone (MR agonist) but now as well as after dexamethasone (GR agonist). The gene discussed is NR3C2; the disease is depressive symptom measurement.