CXCL9 and infection: Whereas the endothelial and glial localization of CXCL9 and CXCL10 producing cells is consistent with a role for these chemokines in the recruitment of inflammatory leucocytes to the site of parasite sequestration (intravascular infiltration without extravasation into the brain parenchyma), further research is required to determine the effect that CXCL10 upregulation might have in neuronal tissue and the effector signals responsible for this response during infection.