Furthermore, several genes (SH3KBP1, CRNN, FLG, S100A7A) related to allergic inflammation [31-34] were either induced in allergic rhinitis patients with or without asthma (SH3KB1) or in allergic rhinitis patients only (CRNN, FLG, S100A7A). Here, SH3KBP1 is linked to allergic rhinitis.