JAK2 and leukemia: Remarkably, irrespective of the Lgl1 genotype of transplanted cells, we observed no significant change in latency in ICN1-ΔRamΔP – (Log rank Mantel-Cox test P = 0.5465), Eμ-Myc- (Log rank Mantel-Cox test P = 0.4607) or TEL-JAK2 induced leukaemia (Log rank Mantel-Cox test P = 0.9071 – Figure 3A, B and C).