In contrast to Hyr1 and Des1, the secreted M. oryzae catalase CatB was not shown to be important for neutralizing plant-derived ROS at the site of penetration but rather for strengthening cell walls [25], while a secreted catalase-peroxidase, CpxB, is needed for neutralizing plant-derived ROS during early infection but not for pathogenicity [26]. The gene discussed is CAT; the disease is infection.