We focused on interpreting the relationship between pneumonia-induced sepsis and four functional SNPs of IFN-γ; these included two SNPs in the 5′ UTR −1616T/C (rs2069705) and −764G/C (rs2069707), as well as two SNPs in the introns +874A/T (rs2430561, intron1) and +3234C/T (rs2069718, intron 3). Here, IFNG is linked to pneumonia.