The two genes may account for less than 30% of the genetic information responsible for heritable breast cancer, indicating that other genes could have a role in hereditary tumors with no BRCA1 or BRCA2 mutations, the so-called non-BRCA1/2 familial tumors (BRCAx) [3], [4], [5], [6]. The gene discussed is BRCA2; the disease is breast cancer.