There are five (rs12190287 (TCF21) rs12413409 (CNNM2), rs1412444 (LIPA), rs1746048 (CXCL12) and rs4977574 (CDKN2A/CDKN2B)) in nine SNPs were significantly associated with MI in the Chinese population under an additive model. The gene discussed is TCF21; the disease is myocardial infarction.