IL10 and alkaline phosphatase measurement: Anti-inflammatory mediators such as interleukins IL-10, IL-11, IL-22, TNF-α receptors, and IL-1 receptor antagonist (IL-1ra) are produced in an effort to limit the inflammatory response; IL-10 and IL-22 have been shown to reduce AP in experimental animal models (Feng et al., 2012; Koike et al., 2012; Xue et al., 2012; Fisic et al., 2013).