We observed evidence of association (P < 0.05) at four loci in the Irish discovery dataset of 1564 cases and 1748 controls; 20p12.2(PAK7 [MIM 608038]); 2cen-q13 (ANKRD36B, COX5B [MIM 123866]; ACTR1B [MIM 605144]); 3p25.1 (MRPS25 [MIM 611987], ZFYVE20 [MIM 609511]) and a previously confirmed schizophrenia risk locus [chr1q.21 (CHD1L [MIM 613039]) locus (8,9)]. Here, RBSN is linked to schizophrenia.