First, we confirmed that the peptide efficiently prevented phosphorylation of the direct CK2 target residue S129 on Akt/PKB (which leads to increased catalytic activity of already activated Akt) [24] in the MO1043 CLL cell line (Figure 1A) and in primary CLL cells (Figure 1B). This evidence concerns the gene AKT1 and B-cell chronic lymphocytic leukemia.