TH and autism: In fact, the original publications cautioned that ‘the TH and HRAS-1 genes are molecularly close, might be in linkage disequilibrium, and could reasonably [both] be considered as good candidate genes' for the ‘positive association between autism and two [(3′ and exon 1)] HRAS markers'.114 Our results suggest that ANO9, located within only 100 kb of HRAS and in the same LD block might be an even better candidate gene than TH, which is located 1.5 Mb and several LD blocks away.