High expression of CSF-1, or c-fms and/or abnormal levels of M-CSF were also reported in chronic inflammatory conditions and ovarian adenocarcinoma, malignant germ cells of ovarian, lung, liver and other cancers at various stages of the disease [3,22,57,93,94,95,96,97,98,99,100,101]. Here, CSF1 is linked to cancer.