Recombinant or isolated gelatinase B/MMP-9 hemopexin domain inhibits gelatinase B/MMP-9 activity [41,163], hampers colorectal cancer cell adhesion and migration [410], inhibits gelatinase B/MMP-9-induced functions in chronic lymphocytic Leukemia B cells [411], and inhibits angiogenesis in glioblastoma xenografts [291]. The gene discussed is MMP9; the disease is glioblastoma.