The other one, was a 53-year-old patient from Neyshabur (the most endemic city in Khorasan province with regard to HTLV-I infection), with history of HAM/TSP since 4 years before the diagnosis of lupus, which was presented with arthritis, leukopenia (2.3×109/L), lymphopenia (0.6×109/L), positive ANA (1/360) and anti-dsDNA (800 U). The gene discussed is BTG3; the disease is Decreased total leukocyte count.