Both Treg and Th2 cells in healthy individuals selectively express CCR4/ Also,the analysis of Foxp3 expression in CD4+CD25+CCR4+ T cells of HAM/TSP patients has shown that the frequency of the Foxp3– population has significantly increased in CD4+CD25+CCR4+ T cells (87). Here, IL2RA is linked to tropical spastic paraparesis.