We also found that secretion of MCP-1/CCL2, ENA-78/CXCL5, and VEGF in TNF-α-stimulated fut1 siRNA-transfected RA synovial fibroblasts was decreased compared to control siRNA-transfected RA synovial fibroblasts. This evidence concerns the gene CXCL5 and rheumatoid arthritis.