When the results for anti-GPIIb/IIIa and anti-GPIb antibody-producing B cells were combined, the positive frequency was slightly increased in patients with primary ITP and SLE, but not in those with liver cirrhosis and post-HSCT, because in the latter cases the anti-GPIb antibody-producing B cells always coexisted with anti-GPIIb/IIIa antibody-producing ones. Here, ITGA2B is linked to systemic lupus erythematosus.