The anti-GPIIb/IIIa antibody response is very common in patients with primary ITP as well as those with various forms of secondary ITP, including thrombocytopenia associated with SLE [8], liver cirrhosis with or without hypersplenism [9], and post-hematopoietic stem-cell transplantation (post-HSCT) [10]. The gene discussed is ITGA2B; the disease is autoimmune thrombocytopenic purpura.