[18], [19] IL-13 supports goblet cell metaplasia and mucus production. [20] Counter-regulation of Th2 cytokines also has therapeutic implications in allergic rhinitis. [21] IL-5 is primarily engaged in the recruitment of eosinophils, which negatively correlate with nasal airflow in asthma and rhinitis patients. [7] In our study, eosinophilic infiltration of the airways occurred to a comparable extent in both, specifically and non-specifically challenged sensitized mouse groups. Here, IL13 is linked to rhinitis.