CD8A and infection: However, from day 12 to day 15, CD8+ T cells from C57BL/6 mice showed a significantly increased degranulation capacity in response to the stimulation with LCMV-gp33 after infection (Figure 7A), which seems to correspond with the increase from day 12 to 15 of the intrahepatic frequency of LCMV-specific T cells (see Figure 5).