In addition, GAS2 was not only deregulated in CML but also in other myeloid proliferative diseases including idiopathic myelofibrosis, polycythemia vera and essential thrombocythemia [26], thus it was interesting to investigate whether GAS2 was required for the improper growth of cells from these hematological disorders as well. Here, GAS2 is linked to essential thrombocythemia.