In addition, GAS2 was not only deregulated in CML but also in other myeloid proliferative diseases including idiopathic myelofibrosis, polycythemia vera and essential thrombocythemia [26], thus it was interesting to investigate whether GAS2 was required for the improper growth of cells from these hematological disorders as well. This evidence concerns the gene GAS2 and acquired polycythemia vera.