Next we used both nucleated cells and CD34+ cells from CML patients in CP and healthy donors to assess the expression of these genes, and the results showed that HNRPDL, UCHL5 and PTK7 had significantly higher expression in CML cells than that in NBM cells (Figure 7C). The gene discussed is UCHL5; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.