Similarly, IL-1β stimulation of PBMCs from RA patients induced a higher increment of MDL-1-expressing monocytes (median 8.8%, IQR7.6–15.7%) compared with stimulation of PBMCs from OA patients (median 5.8%, IQR4.0–6.4%, p<0.01) or from healthy control subjects (median 4.6%, IQR3.7–5.3%, p<0.01; Figure 1F). The gene discussed is CLEC5A; the disease is rheumatoid arthritis.