RASA1 and neoplasm: Although overexpression of RasGAP did increase tumor growth significantly compared to DKO4 cells alone (Figure 5, E & F), it was not able to fully attain the growth rate of the DLD1 parent cell line, indicating that RasGAP alone is not sufficient to rescue tumorigenicity of cells that have lost active KRAS. The mRNA extracted from the xenografts showed that RasGAP expression remained consistent with the cells as they were prior to injection (Figure 5G).