In fact, IFNhigh RA patients displayed higher levels of IL-1β (0.47(1.48) vs. 0.13(0.06) pg/ml, p<0.001), IL-6 (1.93(13.76) vs. 0.75(2.27) pg/ml, p = 0.004), IL-10 (0.65(1.15) vs. 0.26(0.46) pg/ml, p<0.001), MIP-1α (3.29(4.47) vs. 0.00(4.28) pg/ml, p = 0.001) and lower of TGF-β (12.86(4.01) vs. (14.98(5.45) ng/ml, p = 0.025) than IFNlow patients. This evidence concerns the gene CCL3 and rheumatoid arthritis.