TNFAIP8 and cervical carcinoma: Recently, Shi et al. demonstrated that the rs11064 G allele within the TNFAIP8 gene weakens the binding affinity of miR-22 to the TNFAIP8 3′- UTR and is associated with an increased risk of cervical cancer [20], which suggests that miRNA-binding sites are also the hot spots that harbor cervical cancer susceptibility variants.