We compared ratios of the expression levels of Th1-related genes to those of Th2-related genes (IFN-γ/IL-4, IFN-γ/IL-5, TNF-α/IL-4, and TNF-α/IL-5) in footpads of Cr-induced ACD mice (Figure 6A). This evidence concerns the gene IL4 and granular corneal dystrophy type II.