Lavasani et al.[41] demonstrated that the oral administration of three strains of lactobacilli (Lactobacillus paracasei DSM 13434, L. plantarum DSM 15312 and L. plantarum DSM15323) prevented the signs of multiple sclerosis, a T cell mediated inflammatory autoimmune disease affecting the central nervous system, in mice, and that effect correlated with the attenuation of pro-inflammatory Th1 and Th17 cytokines followed by IL-10 induction in the mesenteric lymph nodes (MLN), spleen and blood. The gene discussed is IL10; the disease is multiple sclerosis.