In view of NAT2*5(C481T, rs1799929), NAT2*6 (G590A, rs1799930)and NAT2*7(G857A, rs1799931) mutations accounted for virtually all of the slow acetylator alleles in Asians, we have evaluated the roles of NAT2*5, NAT2*6 and NAT2*7 in the developing of ATLI basing on our community-based TB patients. This evidence concerns the gene NAT2 and tuberculosis.