Forty pediatric T-ALL cases expressed LMO2; 39 T-ALL cases expressed HHEX; 6 cases expressed LMO2 without HHEX and 6 cases expressed HHEX without LMO2; LMO2 and HHEX were concordantly expressed in 34 cases which were statistically enriched for LYL1, MEF2C, and MYCN. These oncogenes were most highly expressed in all 12 cases of Early T-cell Precursor ALL (ETP-ALL) included in this cohort which also clustered together in the LMO2-high group of T-ALLs (see arrows, Figures 4A and S1 in File S1). This evidence concerns the gene MYCN and acute lymphoblastic leukemia.