In the acute phase of stroke activation of cytokines [interleukin-1 beta (IL-1ß), interleukin 6 (IL-6) and tumor necrosis factor-alpha (TNF-α)] [5], chemokines [monocyte chemostatic protein-1 (MCP-1) and macrophage inflammatory protein-1 alpha], [6] matrix metalloproteinases (MMPs) [7], adhesion molecules ICAM-1, P-selectin, E-electin and toxic molecules such as nitric oxide, free radicals, apoptosis (Caspase 3), and stress genes (hsp 70 and hsp 32) occurs. This evidence concerns the gene IL1B and stroke disorder.