The rs2736100 GG homozygote (P = 0.041), cholesterol ≥4.4 mmol/L (P<0.001), low-density lipoprotein ≥2.38 mmol/L (P = 0.002), apolipoprotein B ≥0.69 mmol/L (P<0.001), lipoprotein (a) ≥163 mg/L (P<0.001), uric acid ≥333 μmol/L (P<0.001), homocysteine ≥15.78 μmol/L (P<0.001), total bilirubin ≥13.20 μmol/L (P<0.001), γ-glutamyltransferase ≥33.31 U/L (P<0.001), indirect bilirubin level ≥9.17 μmol/L (P<0.001), and high-density lipoprotein ≤1.08 mmol/L (P = 0.001) were significantly associated with the presence of atherosclerosis by Student's t-tests, Mann–Whitney U tests, and χ2. The gene discussed is APOB; the disease is atherosclerosis.