Further, members of a family with Sensenbrenner syndrome, a ciliopathy characterized by abnormal bony development as well as frequent extraskeletal abnormalities, were found to have a mutation in WDR19 (encoding IFT144); cultured fibroblasts from a Sensenbrenner patient also displayed reduced cilia length compared to cilia from fibroblasts from control cell lines [43]. The gene discussed is WDR19; the disease is cranioectodermal dysplasia.