IFNG and infection: In our previous studies we showed that during acute natural infection of mice, schistosomula-secreted antigens glyceraldehyde 3-phosphate dehydrogenase (SG3PDH) and peroxiredoxin-multiple antigen peptide (PRX-MAP) elicit predominantly Th1 and Th17 immune responses, characterized by the production of interferon-gamma (IFN-γ) and interleukin (IL)-17, and IgG2a and IgG2b antibodies [14].