The results from the meta-analysis indicated no statistically significant association between XRCC1 Arg194Trp polymorphism and tumor response under all the genetic models (T vs. C: OR = 1.15, 95% CI 0.83–1.61; dominant model: OR = 1.23, 95% CI 0.80–1.87; recessive model: OR = 1.11, 95% CI 0.48–2.58)(Table 4). This evidence concerns the gene XRCC1 and neoplasm.