Histone H3 and histone H4 acetylation mediated by histone acetyltransferase lysine (K)-acetyltransferase 3B (KAT3B), and histone H3 dimethyl-lysine 9 (H3K9me2) demethylation catalysed by lysine (K)-specific demethylase 3A (KDM3A) transcriptionally activate ALOX15 in colon cancer cells [20]. This evidence concerns the gene KDM3A and colonic neoplasm.