To determine whether the regulation of PPARγby S. Typhimurium is a transient effect or whether the Lcn2−/− mice are protected at later stages of infection, we infected PPARγVillinCre-, PPARγVillinCre+, Lcn2−/−, and Lcn2+/+ mice with S. Typhimurium and sacrificed them after 72 h. Here, LCN2 is linked to infection.