HIF1A and neoplasm: Next, consecutive sections of fresh NSCLC samples from 30 patients were stained for MME and HIF-1α in order to analyze, whether the expression of both is linked in vivo. Similar to the first series MME staining was found in tumor cells in 21/30 samples (70%) and in stroma cells in 10/30 samples (33.3%; 5 to 20% of stroma cells were MME positive).