PPP1R3C, KCTD11, FAM115C, and HK2, a well-known hypoxia-regulated gene, were up-regulated by hypoxia in a panel of NSCLC cell lines to variable degrees, while MME mRNA showed no increase in expression under hypoxia in any of the cell lines (Figure 3C). Here, PPP1R3C is linked to non-small cell lung carcinoma.