DMD and Duchenne muscular dystrophy: We show that this dmd-MO model is useful for identifying small molecules that rescue the dmd phenotype by showing that the histone deacetylase (HDAC) inhibitor TSA, which has been shown to ameliorate the mdx mouse DMD model 18,19,20,21, can rescue muscle fiber damage similarly in both dmd-MO and dmd mutant larvae.