PGR and neoplasm: In a bivariate analysis, recurrence was significantly associated with the following parameters: tumor grade (P < 0.001), tumor size (HR = 1.9; 95% CI = 1.5, 2.5; P < 0.001), nucleolar prominence (P = 0.044), necrosis (P < 0.001), VEGF expression (HR = 1.6; 95% CI = 1.3, 1.9; P < 0.001), PR expression (HR = 0.7; 95% CI = 0.6, 0.9; P < 0.001), and PI (HR = 1.3; 95% CI = 1.2, 1.4; P < 0.001).